1 | Adam Scharf, PhD | Boston University

Studies Toward the Synthesis of Complex Meroterpenoid Natural Products

2 | Ali Roghanian, PhD | Massachusetts Institute of Technology (MIT)

Novel Humanized Mouse Models of Cancer

3 | Alix Chan | Harvard/Broad

Discovery of a covalent kinase inhibitor from a DNA-encoded small-molecule library x protein library selection

4 | Ameet Shetty, PhD | Harvard Medica School

Spt5 plays vital roles in the control of sense and antisense transcription elongation

5 | Ami Ashar-Patel, PhD | UMass Medical School

Transcriptome wide analysis of 3’ mRNA ends in preeclampsia

6 | Amrendra Ajay, PhD | Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115

CRISPR mediated genome edited cells to study kidney fibrosis

7 | Andrew Wang, PhD | NIBR

Identification and mechanistic characterization of a new v-ATPase inhibitor, Naph62

8 | Archana Boopathy, PhD | Massachusetts Institute of Technology

Sustained immune responses following delivery of a HIV subunit vaccine using silk microneedle skin patches

9 | Cancan Huang, PhD | Harvard University

Tuning of the molecular conductance by single-molecular break junction

10 | Caroline Kotlowski, PhD | MIT Chemical Engineering

A tailored proteo-graphene surface as biosensor for screening chemically similar small molecules inspired by the honeybee’s olfaction

11 | Chiara Pighi, PhD | Department of Pathology, Boston Children's Hospital, Harvard Medical School

FBXO11 is recurrently mutated in Burkitt Lymphoma and its inactivation accelerates lymphomagenesis in Eµ-myc mice.

12 | Chirag Lakhani, PhD | Department of Biomedical Informatics

Building an Exposome API

13 | Christina Tognoni, PhD | Boston University

White matter neurons: New perspectives for Alzheimer’s disease

14 | Claire Doyle, PhD | Boston Children's Hospital & Harvard Medical School

The role of the mucosa in modulation of evoked resposnses in the spinal cord injured rat bladder

15 | Colles Price, PhD | Dana Farber Cancer Institute/Broad Institute of M.I.T. and Harvard

Integrated RNAi and CRISPR screen reveals novel dependencies in ovarian cancer

16 | Cynthia Gubbels, PhD | Boston Children's Hospital

Genome guided management in the NICU

17 | Daniel Ehlinger, PhD | Boston Children's Hospital

Global and cell-type specific disruptions of psychiatric risk gene CACNA1C alter ascending serotonin system activity.

18 | Deborah Flusberg, PhD | Merck Research Laboratories

Identification of G-Quadruplex Binding MYC Inhibitors Using Automated Ligand Identification System (ALIS)

19 | Edward Richards, PhD | Koch Institute

Model-driven design of TAMR inhibitors for therapeutic use in tumor promoting macrophages

20 | Elizabeth Smith | Tufts University School of Medicine

The Whole Tooth and Nothing but the Tooth: Bioengineered GelMA Tooth Bud Constructs for Future Applications in Implant Dentistry

21 | Emmanuel Virot, PhD | EPFL / Harvard

Transition towards buckling in coke cans

22 | Greggory Rice, PhD | Novartis Institutes for Biomedical Research

sTREAT: a fluorescent protein based reporter system for monitoring RNA nuclease processing events in cells

23 | Haihua Xiao, PhD | MIT

Development of Novel Platinum Agents with Unique Mechanism of Action for Drug Delivery

24 | Hicham Mahboubi, PhD | Novartis

Building a reporter system to assess repeat-associated translation: Application to screen genetic modulators of microsatellite expansion disorders

25 | Hyelim Cho, PhD | Novartis

Discovery and elucidation of the anti-melanoma mechanism of liminoid natural products

26 | Ingrid Aries, PhD | Boston Children's Hospital

PRC2 Inactivation Induces Primary Chemotherapy Resistance in T-cell Acute Lymphoblastic Leukemia by Upregulating the TRAP1 Mitochondrial Chaperone

27 | Irina Armean, PhD | MGH/Broad

Naturally occurring human variation suggests LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

28 | Jaclyn Dunphy | Tufts University

Optogenetic control of exocytosis: Gaining a better understanding of the mechanisms underlying schizophrenia

29 | John Santa Maria, PhD | Merck Research Laboratories

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase

30 | Junrui Cheng, PhD | Tufts University

Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization

31 | Keith Bentley, PhD | Massachusetts Institute of Technology

A Novel Methodology for More Efficient Synthesis of Pharmaceutically Relevant Compounds

32 | Kelly (Wen Li) Chen, PhD | MIT

Development of In-Vitro Microphysiological Systems to Interrogate Inter-Tissue Crosstalk for Applications in Disease Modeling and Drug Development

33 | Klaus Bonazza, PhD | Harvard Medical School / Boston Children's Hospital

Mechano-selective activation of a drug glycoprotein

34 | Kristie Hilliard, PhD | Merck

IL-17 Promotes Intestinal Epithelial Homeostasis: Functional Use of Human Intestinal 3D Organoids and Implications for Potential IBD Therapies

35 | Leah Bury, PhD | Whitehead Institute for Biomedical Research

Defining the Molecular Basis for Centromere Transcription

36 | Lei Ji, PhD | Novartis Institutes for Biomedical Research

The SIAH E3 ubiquitin ligases promote Wnt/beta-catenin signaling through mediating Wnt-induced Axin degradation

37 | Leigh Matano | Harvard Medical School

Accelerating the discovery of antibacterial compounds using pathway-directed whole cell screening

38 | Mahsa Zarei, PhD | Brigham and Women's Hospital,Harvard Medical school

IDH1 is post-transcriptionally regulated to promote a pro-survival phenotype in pancreatic cancer cells

39 | Margherita Perillo, PhD | Boston College

Positioning of subsets of nuclei at the neuromuscular and myotendinous junctions in muscles

40 | Maria Montiel, PhD | Marine Biological Laboratory

Correction of the Most Frequent Premature Termination Codon Mutations in CFTR by Site-directed RNA Editing

41 | Md Nurunnabi, PhD | Harvard Medical School-Massachusetts General Hospital

Oral Delivery of Therapeutic Gene Encoding Glucagon-Like Peptide 1 to Treat High Fat Diet-induced Diabetes

42 | Mehrdad Khajavi, PhD | Boston Children's Hospital

Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice

43 | Meltem Isik, PhD | Joslin Diabetes Center, Harvard Medical Shool

Regulation of Alternative Splicing by mTORC1 signaling in vivo

44 | Michael Cuccarese, PhD | Massachusetts General Hospital

Seeing Deeper with molecular probes

45 | Mikael Garabedian | Brandeis University

The F-BAR protein Hof1 and NPF Bud6 comprise a feedback loop for formin control and cellular actin cable assembly

46 | Muhammad Qadri, PhD | Tufts University

Pigeons fail to anticipate the remaining within-session sequence when trained with multiple sequences

47 | Mun Kyung Hwang, PhD | MIT/Koch Institute

The checkpoint kinase-regulated phosphoproteome drives a cytoskeleton-associated adaptive response to chemotherapy

48 | Muthunarayanan Muthiah, PhD | Mass general hospital and Harvard medical school

Therapeutic Effect of Gene loaded Nanoparticle Eluting Coronary Stent on Suppression of Post-Angioplasty Restenosis

49 | Neelakshi Hudda, PhD | Tufts University

Residential Ambient and In-Home Air Quality Impacts of Aviation-Related Emissions

50 | Octavian Bucur, PhD | Beth Israel Deaconess Medical Center, Harvard Medical School

Expansion Pathology: Physical Tissue Expansion for Nanoscale Imaging and Investigation of Clinical Specimens

51 | Parisa Shooshtari, PhD | Broad Institute

Integrative genetic and epigenetic analysis uncovers regulatory mechanisms of autoimmune disease

52 | Pooja Sharma, PhD | Harvard Medical School

Fragment based discovery of protein-protein interaction site ligands of a cytokine signalling pathway: Towards Non-ATP competitive JAK2 inhibitors

53 | Sanjoy Khan, PhD | Harvard School of Dental Medicine

Expression of McCune-Albright Syndrome causing GαsR201H mutation in mesenchymal progenitor cells causes Fibrous Dysplasia in mice

54 | Lindy Kahanovitz-Amir | Mass General Hospital

  • Development of Analog-specific Immunoassays for Pharmacokinetic Studies of Insulin Lispro and Insulin Aspart*

    55 | Sarani Ghoshal, PhD | MGH

    Combination Therapy with a Liver Selective Acetyl-CoA Carboxylase Inhibitor ND-654 and Sorafenib Improves Efficacy in the Treatment of Cirrhotic Rats with Hepatocellular Carcinoma

    56 | Satoru Horiya, PhD | Brandeis University

    Directed evolution of glycopeptides that bind to broadly neutralizing HIV antibodies for HIV vaccine design

    57 | Seungkyu Lee, PhD | Boston Children's Hospital

    Identification of Potassium Channel Subtypes Involved in Human ALS Hyperexcitability by Patch-seq and Patch-RT-qPCR

    58 | Srinivasan Sakthivel, PhD | University of Copenhagen

    Is an unknown functional gene causing heart malformations by birth?

    59 | Sumanta Day, PhD | Massachusetts Institute of Technology

    A genome engineering approach for drug target identification in malaria parasites

    60 | Surya Singh, PhD | MIT

    Label free methods to monitor ultra-violet radiation induced changes in skin cells

    61 | Tamara Zaytouni, PhD | Boston Children's Hospital

    Critical role for the urea cycle in obesity-associated pancreatic cancer

    62 | Terence Wong | Broad Institute

    Comprehensive cistromic characterization of SOX10, a lineage-specific genetic dependency in melanoma, via the integration of functional genomic approaches

    63 | Terence Wong | Broad Institute

    Annual NextGen survey highlights the evolving needs of the postdoc and graduate student community at the Broad Institute

    64 | Tianmin Fu, PhD | Boston Childrens' Hospital

    The triggering of death receptor signaling through helical assembly

    65 | Timothy Calamaras, PhD | Tufts Medical Center

    Mixed lineage kinase 3 (MLK3), a novel PKGIα substrate, prevents maladaptive cardiac structural and functional changes in heart failure.

    66 | Tingyu Liu, PhD | Novartis Institute of Biomedical Research

    An in vitro model to screen immunomodulation reagents for Juvenile Recurrent Respiratory Papillomatosis (JRRP)

    67 | Wei Chou Tseng, PhD | Pfizer

    A schizophrenia-associated SNP in zinc transporter SLC39A8 causes deficits in glutamate receptor activity and elevates the innate immune response

    68 | Wei Liu, PhD | Pfizer

    Mechanistic Insights into the KHK Dependent and Independent Fructose Metabolism

    69 | Weier Qi, PhD | Joslin Diabetes Center

    Activation of Pyruvate Kinase M2 Prevents the Development of Diabetic Nephropathy: Identification of a Novel Target From the Joslin 50-Year Medalist Study

    70 | Xavier Michelet, PhD | Brigham and Women's Hospital

    Obesity Induces Metabolic Reprogramming In Natural Killer Cells Preventing Cytotoxicity Against Tumors

    71 | Xiaojiang Li, PhD | MIT Senseable City Lab

    Mapping urban streetscape environment using Google Street View

    72 | Xuanshi Liu, PhD | Boston Children's Hospital

    Untargeted monitoring external and internal exposures in autism spectrum disorder

    73 | Xuebing Wu, PhD | Whitehead Institute/MIT/HHMI

    Widespread Influence of 3’-end Structures on Mammalian mRNA Processing and Stability

    74 | Yi Wen Kong, PhD | MIT

    Exploiting Rewiring kinase signaling with nanotechnology to augment the efficacy of frontline chemotherapy.

    75 | Yoojin Shin, PhD | MIT

    Development of 3D Alzheimer’s disease-brain blood barrier model

    76 | Yuchun Guo, PhD | MIT Computer Science and Artificial Intelligence Laboratory

    A novel k-mer set memory (KSM) motif representation improves regulatory variant prediction

    77 | Zhongjie Fu, PhD | Boston Children's Hospital / Harvard Medical School

    Fibroblast growth factor 21 restores retinal neuronal function in type 1 diabetic mice